In May 2025, Local Health and Global Profits (LHGP) responded to the UK Department of Health and Social Care’s call for evidence to inform the development of the government’s national cancer plan for England.
This page provides a summary the response. LHGP has drawn on their understanding of the commercial determinants of health, and the response addresses the key areas of prevention, inequalities and priorities for the national cancer plan.
Prevention and awareness
The call for evidence asked for a list of risk factors to be prioritised, with the three ‘most important’ identified.
It is LHGP’s view that all cancer risk factors should be addressed through dedicated resources to improve prevention within the population. There is strong and consistent evidence to link obesity, physical inactivity, UV radiation and air pollution to various forms of cancer, and none should be prioritised as more important than another.
Similarly, alcohol, tobacco and the commercial determinants of health (CDOH) are risk factors which also have robust evidence for their links to cancer. These are the commercial sector activities that affect people’s health, positively or negatively.
Unhealthy commodity industries
The tobacco, alcohol and ultra-processed food industries are examples of unhealthy commodity industries, which shape health both directly and indirectly as a result of their business practices. These activities can be
direct, such as the marketing and sale of unhealthy products;
more indirect, like industry lobbying against duty increases, donating to political campaigns, funding research, and generating doubt in relation to product harms.
Non-communicable diseases (NCDs), such as cancer, are often the result of the physical and social environment, which includes the commercial determinants. These diseases are a major driver of health inequalities. Tackling this major driver will help in reducing the incidence of these diseases, and thus health inequalities.
These system-level challenges require system-level solutions to protect people from harm, reduce health inequalities, and foster healthier models of economic growth.
Reference: The Commercial Determinants of Health (CDOH), adverse policy, influence and conflicts of interest. (Spectrum Consortium, 2021)
The impact of inequalities
Variation in cancer incidence and outcomes exist based on geographical location and socioeconomic background. When considering areas where the government could have the most impact in reducing inequalities in cancer incidence. tackling the commercial determinants of health should be a priority.
Unhealthy commodities, such as tobacco, alcohol and gambling, drive an increased burden of disease for communities, and health harms from unhealthy products are much higher when risk factors are combined, which is more common in disadvantaged groups.
Evidence and references:
Evidence from the EPIC-Norfolk study (PLOS Medicine, 2008)
Holding us back: tobacco, alcohol and unhealthy food and drink (ASH report, 2023)
In Glasgow, the most deprived areas were found to contain the largest number of clusters of alcohol, fast food, tobacco and gambling outlets (Health and Place, 2018)
In England, there are more than six times as many outdoor adverts in the most deprived areas of the country than in the least deprived (Adfree cities report, 2024)
In England, cancer incidence rates are higher in the most deprived populations compared with the least. This difference is generally largest for smoking-related cancer types. This reflects the longstanding higher smoking prevalence in more deprived groups; in 2023, 21.7% of adults living in the poorest areas of England smoked, compared to only 6.2% of those living in the wealthiest areas. (DHSC Fingertips report)
People living in the most deprived areas in England being are 20% more likely to have overweight or obesity and have over twice the risk of alcohol-specific mortality compared to those living in the least deprived areas. (DHSC Fingertips report)
Inequalities in health outcomes among these groups are clearly linked to commercial practices and operators. This represents a fundamental power imbalance with negative health and equity implications. Tackling it should be a priority for the Government in reducing inequalities in health, particularly cancer incidence.
Priorities for the national cancer plan
Interventions that the Government can and should introduce to limit the influence of industry on the population’s diet and facilitate a greater diversity of healthier choices for more people in more places include:
restricting marketing of unhealthy foods to children
mandatory reformulation of unhealthy foods
restricting fast-food outlets near to children’s education settings and playgrounds.
Increasing excise duties
Reducing the affordability of tobacco is recognised to be the most effective way of reducing smoking prevalence. With regard to excised duties on unhealthy products, the evidence suggests the following:
Increasing excise duties on alcohol reduces cases of new alcohol-attributable cancers (Lancet Regional Health Europe, 2021)
Increasing excise duties also increase government revenue (Appl Health Econ Health Policy, 2024) despite claims by the alcohol industry that the opposite is true (Institute of Alcohol Studies, 2024
The higher the escalator above inflation, the greater the impact it has, and the greater the potential to save lives (Spectrum Consortium, 2023).
This provides a win-win situation for public health and the economy, as it also addresses the significant costs associated with tobacco-related illness, such as through productivity loss and strain on healthcare systems.
It is important that price interventions are implemented alongside targeted, accessible and well-resourced cessation services, to ensure that those facing greatest harm are supported.
Protecting resources for population approaches
Local authorities need ring-fenced, long-term funding to deliver vital services which support their populations and reduce health inequalities.
A polluter pays levy and excise taxes are an opportunity to raise the money needed to carry out vital public health interventions, as health is not only a human right but is the foundation on which a thriving economy is built.
The government’s focus should be on population-level approaches to prevention – those that tackle the underlying social and systemic causes of ill-health rather than clinical interventions. These are proven to be more effective at improving health outcomes and are more cost effective (Centre for Health Economics, 2019)
There also continues to be broad public support for a bolder approach to public health policymaking (Health Foundation, 2014).
This emphasises the need for the national cancer plan to focus on prevention and the wider determinants of health in order to effect a step-change in our national approach to cancer prevention.